RAB3GAP2

Across TCGA cell cohorts, RAB3GAP2 mutation is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB3GAP2-associated genes across cancer lineages are KCNK16, CCR8, and GIMAP7. Each is linked with RAB3GAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB3GAP2-to-partner and partner-to-RAB3GAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNK16 grouped by RAB3GAP2-low versus RAB3GAP2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB3GAP2→partner) and Y-score (partner→RAB3GAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	KCNK16 →	+0.071	+5.000	<.001	.006	3	2
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
CNS	GIMAP7 →	+0.054	+4.169	<.001	.008	3	1
CNS	RXFP3 →	+0.063	+4.169	<.001	.008	3	1
CNS	DEFB133 →	+0.035	+5.357	<.001	.001	3	1
LUNG_NSCLC_LUAD	HTN1 →	+0.037	+3.604	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

KCNK16 by RAB3GAP2 expression — PANCREAS

Explore this box plot interactively →