RAB37

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RAB37 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RAB37’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RAB37 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types RAB37 is over-expressed in tumor, although a few such as LUAD and LSCC show the opposite, repressed pattern.

LUAD and LSCC are the cancer types where RAB37 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB37 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADFemaleII,III,IV−0.872<.0019view →
LSCCMaleAll−0.879<.0018view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RAB37–LUAD

Tumor-vs-normal mass-spec protein box plot for RAB37 in LUAD.

Open the LUAD breakdown →

Exploration