RAB35

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB35 protein abundance is significantly associated with the RNA expression of many other genes, with 13,327 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAB35-associated genes across cancer lineages are PPIF, SRSF9, and SUDS3. Each is linked with RAB35 in more than 4 cancer types. Because this analysis shows association rather than direction, both RAB35-to-partner and partner-to-RAB35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAB35 versus PPIF in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB35→partner) and Y-score (partner→RAB35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPPIF →+0.662+0.318<.001<.00135
LSCCSRSF9 →+0.353+0.150.002.00534
UCECSUDS3 →+0.432+0.247.001.00134
OVCOX6A1 →+0.455+0.160.002.00634
LSCCDDX54 →+0.383+0.134<.001.00234
OVPGAM5 →+0.466+0.249.007.00525
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,327 associations by consensus.

RAB35 vs PPIF — BRCA

Per-sample scatter of RAB35 vs PPIF in BRCA (Pearson r = 0.33).

Explore this scatter interactively →

Exploration