RAB35

Across TCGA patient cohorts, RAB35 mutation is significantly associated with the RNA expression of many other genes, with 1,312 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB35-associated genes across cancer lineages are RPS29P32, LINC01040, and RPL31P47. Each is linked with RAB35 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB35-to-partner and partner-to-RAB35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by RAB35-low versus RAB35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB35→partner) and Y-score (partner→RAB35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.427	+2.462	<.001	.004	3	2
SKCM	LINC01040 →	+0.027	+4.212	<.001	.007	3	2
UCEC	RPL31P47 →	+0.329	+2.648	<.001	.001	3	2
BRCA	OFD1P16Y →	+0.129	+9.057	<.001	.003	3	1
COAD	RNU6-694P →	+0.459	+5.893	<.001	.002	3	1
COAD	MIR3158-1 →	+0.580	+5.145	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,312 associations by consensus.

RPS29P32 by RAB35 expression — UCEC

Explore this box plot interactively →