RAB35

Across TCGA cell cohorts, RAB35 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,721 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB35-associated GO terms across cancer lineages are mRNA alternative polyadenylation, CAMP/PKA signal transduction, and Endosomal vesicle fusion. Each is linked with RAB35 in more than 14 cancer types. Because this analysis shows association rather than direction, both RAB35-to-partner and partner-to-RAB35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by RAB35-low versus RAB35-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB35→partner) and Y-score (partner→RAB35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	mRNA alternative polyadenylation →	+0.092	+0.633	<.001	<.001	3	14
BLOOD_Myeloma	CAMP/PKA signal transduction →	+0.177	+0.922	.001	.004	2	15
LARGE_INTESTINE	Endosomal vesicle fusion →	+0.095	+0.799	<.001	<.001	3	14
LARGE_INTESTINE	Positive regulation of TORC2 signaling →	+0.107	+0.828	<.001	<.001	3	13
BONE	Regulation of hippo signaling →	+0.074	+0.475	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Signal transduction in response to DNA damage →	+0.081	+0.804	<.001	.004	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,721 associations by consensus.

mRNA alternative polyadenylation by RAB35 expression — BONE

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