RAB34

Across TCGA patient cohorts, RAB34 mutation is significantly associated with the RNA expression of many other genes, with 597 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RAB34-associated genes across cancer lineages are RNU5F-2P, LINC01796, and CST3. Each is linked with RAB34 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB34-to-partner and partner-to-RAB34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5F-2P grouped by RAB34-low versus RAB34-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB34→partner) and Y-score (partner→RAB34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU5F-2P →	+0.629	+3.252	<.001	.009	3	2
STAD	LINC01796 →	+0.191	+3.568	.009	.009	3	2
COAD	CST3 →	-1.086	-3.446	<.001	.005	3	2
HNSC	RPL17P35 →	+0.091	+5.435	<.001	.005	3	2
HNSC	MIR4316 →	+0.835	+5.368	<.001	.005	3	2
COAD	EDARADD →	+0.413	+3.499	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 597 associations by consensus.

RNU5F-2P by RAB34 expression — STAD

Explore this box plot interactively →