RAB34

Across TCGA cell cohorts, RAB34 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB34-associated genes across cancer lineages are 50869, MK-2206, and AZD2014. Each is linked with RAB34 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB34-to-partner and partner-to-RAB34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by RAB34-low versus RAB34-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB34→partner) and Y-score (partner→RAB34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	50869 →	+0.472	+2.649	.025	.046	2	1
LARGE_INTESTINE	MK-2206 →	+0.561	+2.646	.035	.047	1	1
LARGE_INTESTINE	AZD2014 →	+0.607	+2.649	.019	.046	1	1
LARGE_INTESTINE	AZD1208 →	+0.401	+2.649	.019	.046	1	1
LARGE_INTESTINE	Uprosertib →	+0.605	+2.646	.046	.047	1	1
LARGE_INTESTINE	PCI-34051 →	+0.557	+2.646	.003	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

50869 by RAB34 expression — LARGE_INTESTINE

Explore this box plot interactively →