RAB33A

Across TCGA patient cohorts, RAB33A mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB33A-associated genes across cancer lineages are aDC, CD8+ Tcm, and Memory B-cells. Each is linked with RAB33A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB33A-to-partner and partner-to-RAB33A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by RAB33A-low versus RAB33A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB33A→partner) and Y-score (partner→RAB33A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.088	+1.768	.005	.049	3	2
UCEC	CD8+ Tcm →	+0.034	+3.061	<.001	<.001	3	2
UCEC	Memory B-cells →	+0.027	+1.788	.016	.017	3	2
UCEC	CD8+ naive T-cells →	+0.023	+2.839	.046	.034	3	1
UCEC	CD8+ T-cells →	+0.022	+2.582	<.001	.003	3	1
UCEC	Basophils →	+0.155	+1.700	.031	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

aDC by RAB33A expression — UCEC

Explore this box plot interactively →