RAB2B

Across TCGA pan-cancer cohorts, RAB2B mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RAB2B data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RAB2B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB2B expression acts as an unfavorable survival marker, although some lineages such as GBM and UCEC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where RAB2B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.873	1.000	.019	18	view →
PDAC	DFS	Quartile	All	0.309	0.617	.002	16	view →
LUAD	OS	Quartile	II,III,IV	0.350	0.893	.008	15	view →
GBM	DFS	Median	All	0.838	0.664	.005	6	view →
HNSC	OS	Tertile	III,IV	0.331	1.000	.040	4	view →
UCEC	OS	Median	All	0.966	0.841	.014	4	view →
CCRCC	OS	Quartile	III,IV	0.899	0.557	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RAB2B–COAD (DFS)

Open the COAD breakdown →