RAB2B

Across TCGA patient cohorts, RAB2B mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB2B-associated genes across cancer lineages are PHKG1P1, RNA5SP517, and MIR6766. Each is linked with RAB2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB2B-to-partner and partner-to-RAB2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHKG1P1 grouped by RAB2B-low versus RAB2B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB2B→partner) and Y-score (partner→RAB2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	PHKG1P1 →	+0.052	+5.144	<.001	.003	3	2
BLCA	RNA5SP517 →	+0.263	+7.640	<.001	.009	3	2
UCEC	MIR6766 →	+0.415	+3.358	<.001	.006	3	1
UCEC	RNA5SP412 →	+1.212	+3.289	<.001	.001	3	1
LUAD	MIR489 →	+0.406	+7.930	<.001	.008	3	1
BLCA	MIR8485 →	+0.326	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

PHKG1P1 by RAB2B expression — CESC

Explore this box plot interactively →