RAB2B

Across TCGA patient cohorts, RAB2B mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB2B-associated genes across cancer lineages are NK cells, Fibroblasts, and Endothelial cells. Each is linked with RAB2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB2B-to-partner and partner-to-RAB2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NK cells grouped by RAB2B-low versus RAB2B-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB2B→partner) and Y-score (partner→RAB2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NK cells →	+0.006	+5.597	<.001	.040	3	1
CESC	Fibroblasts →	+0.016	+5.144	<.001	.003	3	1
UCEC	Endothelial cells →	-0.050	-2.957	.024	.037	1	1
UCEC	lymphatic Endothelial cells →	-0.028	-2.946	.040	.037	1	1
UCEC	mv Endothelial cells →	-0.034	-2.989	.012	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

NK cells by RAB2B expression — STAD

Explore this box plot interactively →