RAB2B

Across TCGA cell cohorts, RAB2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,158 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB2B-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Epigenetic regulation of gene expression, and Establishment of vesicle localization. Each is linked with RAB2B in more than 13 cancer types. Because this analysis shows association rather than direction, both RAB2B-to-partner and partner-to-RAB2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by RAB2B-low versus RAB2B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB2B→partner) and Y-score (partner→RAB2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.053	+0.765	.001	.002	3	14
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.067	+0.797	<.001	.008	3	14
LUNG_SCLC	Establishment of vesicle localization →	+0.050	+0.779	.005	.002	3	14
KIDNEY	Positive regulation of mRNA metabolic process →	+0.059	+0.818	.001	.003	3	13
KIDNEY	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.062	+0.820	<.001	<.001	3	13
SOFT_TISSUE	Golgi vesicle transport →	+0.064	+0.856	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,158 associations by consensus.

Negative regulation of gene expression, epigenetic by RAB2B expression — UPPER_AERODIGESTIVE_TRACT

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