RAB28

Across TCGA pan-cancer cohorts, RAB28 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RAB28 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RAB28 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RAB28 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where RAB28 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.837	0.355	.001	16	view →
LSCC	DFS	Median	II,III,IV	0.506	0.861	.002	7	view →
CCRCC	DFS	Tertile	All	1.000	0.874	.018	4	view →
UCEC	OS	Quartile	II,III,IV	0.315	0.891	.038	4	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	3	view →
HNSC	DFS	Tertile	III,IV	0.900	0.692	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RAB28–LUAD (DFS)

Open the LUAD breakdown →