RAB28

Across TCGA patient cohorts, RAB28 mutation is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB28-associated genes across cancer lineages are RNA5SP431, GTF2IP2, and WHAMM. Each is linked with RAB28 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB28-to-partner and partner-to-RAB28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP431 grouped by RAB28-low versus RAB28-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB28→partner) and Y-score (partner→RAB28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP431 →	+0.459	+2.773	<.001	.004	3	2
LUSC	GTF2IP2 →	+0.244	+5.150	.007	.001	3	2
UCEC	WHAMM →	+0.422	+2.523	.001	.009	3	1
UCEC	CXCL13 →	+1.667	+3.584	.002	.002	3	1
UCEC	CPAMD8 →	-1.260	-2.785	.002	.003	3	1
UCEC	MED27 →	+0.429	+3.532	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

RNA5SP431 by RAB28 expression — UCEC

Explore this box plot interactively →