RAB28

Across TCGA cell cohorts, RAB28 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,568 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB28-associated GO terms across cancer lineages are Centrosome cycle, Microtubule organizing center organization, and Centrosome duplication. Each is linked with RAB28 in more than 12 cancer types. Because this analysis shows association rather than direction, both RAB28-to-partner and partner-to-RAB28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by RAB28-low versus RAB28-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB28→partner) and Y-score (partner→RAB28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Centrosome cycle →	+0.070	+0.714	<.001	<.001	3	13
BLOOD_Leukemia	Microtubule organizing center organization →	+0.066	+0.640	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Centrosome duplication →	+0.074	+0.689	.001	.001	3	12
URINARY_TRACT	Positive regulation of organelle assembly →	+0.055	+0.634	<.001	.004	2	13
SOFT_TISSUE	Regulation of chromosome condensation →	+0.163	+0.730	.004	.001	3	11
LARGE_INTESTINE	Protein localization to cilium →	+0.048	+0.678	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,568 associations by consensus.

Centrosome cycle by RAB28 expression — BLOOD_Leukemia

Explore this box plot interactively →