RAB26

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB26 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB26-associated genes across cancer lineages are RNA5SP162, MIR4510, and RN7SL847P. Each is linked with RAB26 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB26-to-partner and partner-to-RAB26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP162 grouped by RAB26-low versus RAB26-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB26→partner) and Y-score (partner→RAB26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP162 →+0.771+5.103<.001.00831
CESCMIR4510 →+0.400+6.342<.001.00131
CESCRN7SL847P →+0.260+5.010<.001.00931
HNSCRNU6-492P →+0.478+7.954<.001.00831
HNSCRNU4-37P →+0.266+7.954<.001.00831
HNSCRNU4-26P →+0.268+7.954<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

RNA5SP162 by RAB26 expression — CESC

Box plot of RNA5SP162 in RAB26-low vs RAB26-high samples in CESC.

Explore this box plot interactively →

Exploration