RAB26

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB26 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB26-associated genes across cancer lineages are TMCO5A and OR10W1. Each is linked with RAB26 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB26-to-partner and partner-to-RAB26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by RAB26-low versus RAB26-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB26→partner) and Y-score (partner→RAB26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETMCO5A →+0.026+5.415<.001.00431
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TMCO5A by RAB26 expression — LARGE_INTESTINE

Box plot of TMCO5A in RAB26-low vs RAB26-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration