RAB24

Across TCGA patient cohorts, RAB24 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB24-associated genes across cancer lineages are eEF2, ERK2, and INPP4B. Each is linked with RAB24 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB24-to-partner and partner-to-RAB24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by RAB24-low versus RAB24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB24→partner) and Y-score (partner→RAB24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.536	+3.321	.004	.010	3	1
UCEC	ERK2 →	+0.201	+3.000	.046	.036	3	1
UCEC	INPP4B →	-0.408	-3.308	.016	.010	3	1
UCEC	PDK1_pS241 →	+0.242	+3.335	.006	.005	3	1
UCEC	PRDX1 →	+0.214	+3.000	.047	.036	3	1
UCEC	PCNA →	+0.290	+3.169	.010	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

eEF2 by RAB24 expression — UCEC

Explore this box plot interactively →