RAB23

Across TCGA patient cohorts, RAB23 mutation is significantly associated with the RNA expression of many other genes, with 791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB23-associated genes across cancer lineages are RNA5SP164, RNA5SP72, and NDUFAF2P1. Each is linked with RAB23 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB23-to-partner and partner-to-RAB23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP164 grouped by RAB23-low versus RAB23-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB23→partner) and Y-score (partner→RAB23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP164 →	+0.244	+8.471	<.001	.005	3	2
UCEC	RNA5SP72 →	+0.286	+2.572	<.001	.007	3	2
UCEC	NDUFAF2P1 →	+0.752	+2.711	<.001	.003	3	1
UCEC	LINC01943 →	+0.533	+2.732	.001	.003	3	1
BRCA	RNU6-148P →	+0.276	+7.731	<.001	.009	3	1
UCEC	COX5A →	+0.467	+2.711	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 791 associations by consensus.

RNA5SP164 by RAB23 expression — BRCA

Explore this box plot interactively →