RAB22A

Across TCGA patient cohorts, RAB22A mutation is significantly associated with the RNA expression of many other genes, with 2,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB22A-associated genes across cancer lineages are RNA5SP414, RNA5SP412, and TRIM51EP. Each is linked with RAB22A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB22A-to-partner and partner-to-RAB22A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by RAB22A-low versus RAB22A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB22A→partner) and Y-score (partner→RAB22A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.409	+2.053	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.502	+1.765	<.001	.001	3	2
BLCA	TRIM51EP →	+0.059	+5.106	.009	.008	3	2
BRCA	RNA5SP416 →	+1.006	+8.471	<.001	.005	3	2
BRCA	MIR4307 →	+0.325	+7.731	<.001	.009	3	2
BRCA	RNA5SP419 →	+0.898	+7.731	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,799 associations by consensus.

RNA5SP414 by RAB22A expression — UCEC

Explore this box plot interactively →