RAB22A

Across TCGA cell cohorts, RAB22A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB22A-associated genes across cancer lineages are GKN1, SYCN, and OR6Q1. Each is linked with RAB22A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB22A-to-partner and partner-to-RAB22A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKN1 grouped by RAB22A-low versus RAB22A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB22A→partner) and Y-score (partner→RAB22A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GKN1 →	+0.078	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SYCN →	+0.047	+5.539	<.001	.003	3	1
LARGE_INTESTINE	OR6Q1 →	+0.030	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GKN1 by RAB22A expression — BLOOD_Leukemia

Explore this box plot interactively →