RAB20

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB20 protein abundance is significantly associated with the RNA expression of many other genes, with 10,253 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAB20-associated genes across cancer lineages are TM9SF2, NAXD, and KIF3C. Each is linked with RAB20 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAB20-to-partner and partner-to-RAB20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAB20 versus TM9SF2 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB20→partner) and Y-score (partner→RAB20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTM9SF2 →+0.643+0.443.003.00234
BRCANAXD →+0.703+0.500<.001<.00134
UCECKIF3C →-0.705-0.361.001.00234
OVCARS2 →+0.486+0.499<.001<.00133
OVBRSK1 →-0.937-0.410.001.00133
LSCCZNF658 →-0.517-0.255<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,253 associations by consensus.

RAB20 vs TM9SF2 — OV

Per-sample scatter of RAB20 vs TM9SF2 in OV (Pearson r = 0.38).

Explore this scatter interactively →

Exploration