RAB20

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB20 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAB20-associated genes across cancer lineages are OR10W1, OR9A2, and AVP. Each is linked with RAB20 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB20-to-partner and partner-to-RAB20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by RAB20-low versus RAB20-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB20→partner) and Y-score (partner→RAB20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaOR10W1 →+0.032+5.643<.001.00231
BLOOD_LymphomaOR9A2 →+0.022+5.209<.001.00531
LARGE_INTESTINEAVP →+0.085+5.217<.001<.00131
LARGE_INTESTINEELOA3DP →+0.039+4.273<.001.00631
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10W1 by RAB20 expression — BLOOD_Lymphoma

Box plot of OR10W1 in RAB20-low vs RAB20-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration