RAB1B

Across TCGA pan-cancer cohorts, RAB1B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB1B data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RAB1B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB1B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where RAB1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.344	0.742	.003	42	view →
CCRCC	DFS	Tertile	All	0.974	0.862	.015	11	view →
LSCC	OS	Median	All	0.697	0.890	.017	6	view →
PDAC	DFS	Tertile	II,III,IV	0.260	0.468	.049	2	view →
HNSC	OS	Tertile	All	0.924	0.802	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB1B–LUAD (DFS)

Open the LUAD breakdown →