RAB19

Across TCGA patient cohorts, RAB19 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB19-associated genes across cancer lineages are eIF4E, Rad50, and Annexin-1. Each is linked with RAB19 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB19-to-partner and partner-to-RAB19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by RAB19-low versus RAB19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB19→partner) and Y-score (partner→RAB19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.298	+2.820	.014	.035	3	1
UCEC	Rad50 →	-0.322	-3.000	.021	.037	3	1
UCEC	Annexin-1 →	+1.022	+2.827	<.001	.035	3	1
UCEC	BRD4 →	+0.369	+3.007	.017	.019	3	1
UCEC	STAT3_pY705 →	-0.442	-3.000	.003	.037	1	2
UCEC	p62 Lck ligand →	+0.488	+3.000	.009	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

eIF4E by RAB19 expression — UCEC

Explore this box plot interactively →