RAB18

Across TCGA patient cohorts, RAB18 protein abundance is significantly associated with the RNA expression of many other genes, with 12,572 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RAB18-associated genes across cancer lineages are ACBD5, WAC, and RBMS3. Each is linked with RAB18 in more than 4 cancer types. Because this analysis shows association rather than direction, both RAB18-to-partner and partner-to-RAB18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAB18 versus ACBD5 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB18→partner) and Y-score (partner→RAB18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACBD5 →	+0.427	+0.488	.001	<.001	3	5
UCEC	WAC →	+0.444	+0.344	<.001	.005	3	5
BRCA	RBMS3 →	-0.610	-0.330	.001	.005	3	4
HNSC	ZNF559 →	-0.847	-0.512	<.001	<.001	3	4
BRCA	IDI1 →	+0.626	+0.359	.001	.001	3	4
COAD	CUL2 →	+0.435	+0.239	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,572 associations by consensus.

RAB18 vs ACBD5 — LSCC

Explore this scatter interactively →