RAB18

Across TCGA patient cohorts, RAB18 mutation is significantly associated with the RNA expression of many other genes, with 2,934 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB18-associated genes across cancer lineages are PDE4DIPP8, RNU6-1082P, and MIR98. Each is linked with RAB18 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB18-to-partner and partner-to-RAB18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDE4DIPP8 grouped by RAB18-low versus RAB18-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB18→partner) and Y-score (partner→RAB18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	PDE4DIPP8 →	+0.034	+5.091	<.001	.003	3	2
UCEC	RNU6-1082P →	+0.178	+2.464	<.001	.007	3	2
UCEC	MIR98 →	+0.197	+2.123	.005	.009	3	2
UCEC	MIR4797 →	+0.336	+2.048	.003	.004	3	2
UCEC	ATP6V1E1P2 →	+0.159	+2.376	<.001	<.001	3	2
COAD	MIR4524B →	+0.603	+5.790	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,934 associations by consensus.

PDE4DIPP8 by RAB18 expression — LIHC

Explore this box plot interactively →