Across TCGA pan-cancer cohorts, RAB17 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RAB17 data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RAB17 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RAB17 expression acts as an unfavorable survival marker.
DLBC are the cancer types where RAB17 Mutation most reproducibly stratifies survival.