RAB17

Across TCGA patient cohorts, RAB17 mutation is significantly associated with the RNA expression of many other genes, with 1,217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB17-associated genes across cancer lineages are RNA5SP252, TSPY24P, and RNU6-627P. Each is linked with RAB17 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB17-to-partner and partner-to-RAB17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP252 grouped by RAB17-low versus RAB17-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB17→partner) and Y-score (partner→RAB17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP252 →	+0.583	+6.438	<.001	.001	3	2
LUSC	TSPY24P →	+0.135	+5.548	.002	.004	3	2
SKCM	RNU6-627P →	+0.333	+7.816	<.001	.008	3	2
UCEC	MTND4LP22 →	+0.180	+2.801	<.001	.005	3	2
UCEC	ZNF852 →	+0.518	+3.346	<.001	.005	3	1
UCEC	MIGA1 →	+0.616	+3.212	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,217 associations by consensus.

RNA5SP252 by RAB17 expression — LUSC

Explore this box plot interactively →