RAB17

Across TCGA cell cohorts, RAB17 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,125 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RAB17-associated GO terms across cancer lineages are Immunoglobulin transcytosis in epithelial cells, Serotonin secretion, and Serotonin production involved in inflammatory response. Each is linked with RAB17 in more than 10 cancer types. Because this analysis shows association rather than direction, both RAB17-to-partner and partner-to-RAB17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin transcytosis in epithelial cells grouped by RAB17-low versus RAB17-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB17→partner) and Y-score (partner→RAB17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Immunoglobulin transcytosis in epithelial cells →	+1.284	+2.223	.001	.009	3	11
URINARY_TRACT	Serotonin secretion →	+1.714	+2.893	<.001	<.001	3	10
URINARY_TRACT	Serotonin production involved in inflammatory response →	+1.714	+2.893	<.001	<.001	3	10
URINARY_TRACT	Serotonin secretion involved in inflammatory response →	+1.714	+2.893	<.001	<.001	3	10
OVARY	Cytotoxic T cell degranulation →	+0.286	+2.416	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Sensory perception of salty taste →	+1.539	+2.534	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,125 associations by consensus.

Immunoglobulin transcytosis in epithelial cells by RAB17 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →