RAB15

Across TCGA patient cohorts, RAB15 mutation is significantly associated with the RNA expression of many other genes, with 3,758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB15-associated genes across cancer lineages are RNA5SP422, MIR1298, and RNA5SP412. Each is linked with RAB15 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB15-to-partner and partner-to-RAB15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by RAB15-low versus RAB15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB15→partner) and Y-score (partner→RAB15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.681	+2.130	<.001	<.001	3	3
HNSC	MIR1298 →	+0.268	+7.954	<.001	.008	3	2
UCEC	RNA5SP412 →	+0.496	+1.719	<.001	.006	3	2
UCEC	RNA5SP410 →	+0.657	+2.467	<.001	<.001	3	2
UCEC	RNA5SP413 →	+1.127	+2.384	<.001	<.001	3	2
UCEC	RNA5SP417 →	+0.573	+2.811	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,758 associations by consensus.

RNA5SP422 by RAB15 expression — UCEC

Explore this box plot interactively →