RAB15

Across TCGA cell cohorts, RAB15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,699 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAB15-associated GO terms across cancer lineages are Copper ion export, Peptidyl-threonine phosphorylation, and Peptidyl-threonine modification. Each is linked with RAB15 in more than 11 cancer types. Because this analysis shows association rather than direction, both RAB15-to-partner and partner-to-RAB15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by RAB15-low versus RAB15-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB15→partner) and Y-score (partner→RAB15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Copper ion export →	-0.180	-1.352	<.001	<.001	3	12
OESOPHAGUS	Peptidyl-threonine phosphorylation →	+0.098	+1.676	.001	<.001	3	10
OESOPHAGUS	Peptidyl-threonine modification →	+0.098	+1.676	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleotide-excision repair →	+0.095	+1.510	<.001	<.001	3	9
SOFT_TISSUE	Protein localization to cytoplasmic stress granule →	+0.087	+0.994	<.001	<.001	3	9
URINARY_TRACT	Signal transduction in absence of ligand →	+0.130	+1.893	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,699 associations by consensus.

Copper ion export by RAB15 expression — LARGE_INTESTINE

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