RAB13

Across TCGA patient cohorts, RAB13 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB13-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and G6PD. Each is linked with RAB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB13-to-partner and partner-to-RAB13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by RAB13-low versus RAB13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB13→partner) and Y-score (partner→RAB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.125	-2.295	.002	.033	3	1
UCEC	A-Raf_pS299 →	-0.164	-3.584	<.001	.002	3	1
UCEC	G6PD →	-0.298	-1.807	.025	.027	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.433	+2.009	.014	.017	3	1
UCEC	Ku80 →	+0.280	+3.183	.004	.009	3	1
UCEC	MEK1 →	+0.514	+3.700	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

14-3-3_beta by RAB13 expression — UCEC

Explore this box plot interactively →