RAB11FIP3

Across TCGA pan-cancer cohorts, RAB11FIP3 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RAB11FIP3 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RAB11FIP3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RAB11FIP3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, UCEC, and HNSC are the cancer types where RAB11FIP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.928	0.105	.006	33	view →
UCEC	DFS	Tertile	II,III,IV	1.000	0.351	.004	24	view →
HNSC	DFS	Median	All	0.907	0.601	.008	12	view →
GBM	DFS	Tertile	All	0.523	0.206	.021	4	view →
LUAD	DFS	Quartile	III,IV	0.886	0.446	.006	3	view →
PDAC	DFS	Tertile	II,III,IV	0.711	0.928	.048	1	view →
LSCC	DFS	Tertile	All	0.862	1.000	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RAB11FIP3–CCRCC (DFS)

Open the CCRCC breakdown →