RAB11FIP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB11FIP2 mutation is significantly associated with the RNA expression of many other genes, with 3,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP2-associated genes across cancer lineages are RNU6-227P, KRTAP9-6, and CDK2AP2P3. Each is linked with RAB11FIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11FIP2-to-partner and partner-to-RAB11FIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-227P grouped by RAB11FIP2-low versus RAB11FIP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP2→partner) and Y-score (partner→RAB11FIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNU6-227P →+0.374+6.639<.001.00132
HNSCKRTAP9-6 →+0.043+4.761<.001.00132
LUSCCDK2AP2P3 →+0.179+4.392.009.00632
LUSCRNU6-1137P →+0.324+4.978<.001.00532
LUSCRNA5SP402 →+0.600+4.503<.001.00532
LUSCRNA5SP415 →+0.841+5.733<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,892 associations by consensus.

RNU6-227P by RAB11FIP2 expression — BRCA

Box plot of RNU6-227P in RAB11FIP2-low vs RAB11FIP2-high samples in BRCA.

Explore this box plot interactively →

Exploration