RAB11FIP2

Across TCGA patient cohorts, RAB11FIP2 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP2-associated genes across cancer lineages are c-Met_pY1235, Annexin_VII, and ASNS. Each is linked with RAB11FIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP2-to-partner and partner-to-RAB11FIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Met_pY1235 grouped by RAB11FIP2-low versus RAB11FIP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP2→partner) and Y-score (partner→RAB11FIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Met_pY1235 →	+0.049	+1.530	.028	.004	3	3
UCEC	Annexin_VII →	-0.105	-1.125	.012	.033	3	2
UCEC	ASNS →	+0.394	+2.999	<.001	<.001	3	2
UCEC	C-Raf →	+0.182	+1.754	<.001	.001	3	2
UCEC	14-3-3_beta →	-0.087	-1.558	.004	.015	3	1
UCEC	EGFR_pY1068 →	-0.265	-1.754	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

c-Met_pY1235 by RAB11FIP2 expression — UCEC

Explore this box plot interactively →