RAB11FIP2

Across TCGA cell cohorts, RAB11FIP2 mutation is significantly associated with the mutation status of many other genes, with 1,760 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB11FIP2-associated genes across cancer lineages are LAMC1, ERF, and PHLDB1. Each is linked with RAB11FIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP2-to-partner and partner-to-RAB11FIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LAMC1 grouped by RAB11FIP2-low versus RAB11FIP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP2→partner) and Y-score (partner→RAB11FIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LAMC1 →	+3.339	+4.662	.003	.003	1	3
BLOOD_Lymphoma	ERF →	+4.429	+5.247	.005	.005	1	3
LARGE_INTESTINE	PHLDB1 →	+2.000	+2.662	.008	.008	1	3
BLOOD_Lymphoma	PC →	+4.429	+5.247	.005	.005	1	3
BLOOD_Lymphoma	ATP6V0A2 →	+4.429	+5.247	.005	.005	1	3
LARGE_INTESTINE	OTOF →	+1.777	+2.963	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,760 associations by consensus.

LAMC1 by RAB11FIP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →