RAB11FIP2

Across TCGA cell cohorts, RAB11FIP2 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAB11FIP2-associated genes across cancer lineages are Dabrafenib, AZD3514, and LCL161. Each is linked with RAB11FIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB11FIP2-to-partner and partner-to-RAB11FIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dabrafenib grouped by RAB11FIP2-low versus RAB11FIP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP2→partner) and Y-score (partner→RAB11FIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Dabrafenib →	+0.778	+2.678	.019	.037	3	1
LARGE_INTESTINE	AZD3514 →	+0.366	+2.649	.021	.046	3	1
LARGE_INTESTINE	LCL161 →	+0.415	+2.672	.010	.039	3	1
LARGE_INTESTINE	PLX-4720 →	+0.584	+2.646	.031	.047	2	1
LARGE_INTESTINE	Mirin →	+0.380	+2.646	.045	.047	2	1
LARGE_INTESTINE	Luminespib →	+0.751	+2.646	.012	.047	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Dabrafenib by RAB11FIP2 expression — LARGE_INTESTINE

Explore this box plot interactively →