RAB11FIP1

Across TCGA pan-cancer cohorts, RAB11FIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB11FIP1 data layer compared with 29 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RAB11FIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAB11FIP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

PDAC, UCEC, and LSCC are the cancer types where RAB11FIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.367	0.891	.003	29	view →
UCEC	OS	Median	II,III,IV	1.000	0.609	.008	16	view →
LSCC	DFS	Median	II,III,IV	1.000	0.854	.002	13	view →
HNSC	OS	Quartile	IV	0.945	0.594	.029	2	view →
LUAD	DFS	Median	III,IV	0.908	0.605	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB11FIP1–PDAC (DFS)

Open the PDAC breakdown →