RAB11FIP1

Across TCGA patient cohorts, RAB11FIP1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB11FIP1-associated genes across cancer lineages are Annexin-1, Caspase-7-cleavedD198, and Caveolin-1. Each is linked with RAB11FIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB11FIP1-to-partner and partner-to-RAB11FIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by RAB11FIP1-low versus RAB11FIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB11FIP1→partner) and Y-score (partner→RAB11FIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.626	+3.169	<.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.555	+2.019	.001	.001	3	3
LUAD	Caveolin-1 →	-0.900	-3.169	.017	.019	3	2
BLCA	PI3K-p85 →	+0.208	+2.820	.045	.035	3	2
UCEC	eIF4E →	+0.177	+1.584	.004	.002	3	2
SKCM	GAPDH →	+0.498	+2.087	.026	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Annexin-1 by RAB11FIP1 expression — UCEC

Explore this box plot interactively →