RAB10

Across TCGA pan-cancer cohorts, RAB10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RAB10 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RAB10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RAB10 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LUAD, and GBM are the cancer types where RAB10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.818	0.521	.001	82	view →
LUAD	OS	Quartile	II,III,IV	0.342	1.000	.005	22	view →
GBM	DFS	Tertile	All	0.245	0.576	.002	19	view →
PDAC	DFS	Quartile	All	0.275	0.525	.021	5	view →
CCRCC	OS	Tertile	All	0.717	1.000	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RAB10–HNSC (DFS)

Open the HNSC breakdown →