Across TCGA patient cohorts, R3HDM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,237 significant associations in total. GBM shows the largest number of these associations.

The most reproducible R3HDM4-associated proteins across cancer lineages are CARM1, MICAL3_S1371, and DOHH. Each is linked with R3HDM4 in more than 4 cancer types. Because this analysis shows association rather than direction, both R3HDM4-to-partner and partner-to-R3HDM4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDM4→partner) and Y-score (partner→R3HDM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CARM1 →	+0.375	+0.568	<.001	<.001	3	5
CCRCC	MICAL3_S1371 →	+0.483	+0.229	.002	.007	3	4
UCEC	DOHH →	+0.228	+0.497	<.001	.003	2	5
LSCC	KHSRP →	+0.256	+0.356	<.001	.005	3	4
OV	MISP_S471 →	+1.531	+0.570	.001	.003	3	4
CCRCC	SYNE2_S4136 →	+0.633	+0.292	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,237 associations by consensus.

Exploration

R3HDM4 survival (RNA) · tumor vs normal (RNA) · all R3HDM4 data types