Across TCGA patient cohorts, R3HDM4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,587 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible R3HDM4-associated genes across cancer lineages are PCMTD1P3, IFNAR1, and IQGAP2. Each is linked with R3HDM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both R3HDM4-to-partner and partner-to-R3HDM4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDM4→partner) and Y-score (partner→R3HDM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCMTD1P3 →	+2.097	+0.504	.001	.005	3	2
GBM	IFNAR1 →	-0.424	-0.502	.003	<.001	3	2
COAD	IQGAP2 →	-0.700	-0.374	.004	<.001	3	2
COAD	STXBP5 →	-0.460	-0.388	.002	.005	3	2
COAD	MARCHF3 →	-0.678	-0.400	<.001	<.001	3	2
GBM	PCDHB13 →	-1.028	-0.371	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,587 associations by consensus.

Exploration

R3HDM4 survival (RNA) · tumor vs normal (RNA) · all R3HDM4 data types