Across TCGA cell cohorts, R3HDM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,583 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible R3HDM4-associated GO terms across cancer lineages are Cytoplasm protein quality control, Cytoplasm protein quality control by the ubiquitin-proteasome system, and Positive regulation of autophagy. Each is linked with R3HDM4 in more than 14 cancer types. Because this analysis shows association rather than direction, both R3HDM4-to-partner and partner-to-R3HDM4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HDM4→partner) and Y-score (partner→R3HDM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoplasm protein quality control →	+0.162	+0.882	<.001	<.001	3	15
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.180	+0.894	<.001	<.001	3	15
URINARY_TRACT	Positive regulation of autophagy →	+0.047	+0.779	<.001	<.001	3	12
CNS	Regulation of blood vessel branching →	+0.118	+0.689	.001	<.001	3	12
BLOOD_Lymphoma	Positive regulation of blood vessel branching →	+0.169	+1.062	<.001	<.001	3	11
URINARY_TRACT	Glucose homeostasis →	+0.081	+0.869	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,583 associations by consensus.

Exploration

R3HDM4 survival (RNA) · tumor vs normal (RNA) · all R3HDM4 data types