R3HCC1L

Across TCGA patient cohorts, R3HCC1L mutation is significantly associated with the RNA expression of many other genes, with 2,719 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible R3HCC1L-associated genes across cancer lineages are OR5D3P, AKR1B1P3, and MIR549A. Each is linked with R3HCC1L in more than 2 cancer types. Because this analysis shows association rather than direction, both R3HCC1L-to-partner and partner-to-R3HCC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5D3P grouped by R3HCC1L-low versus R3HCC1L-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HCC1L→partner) and Y-score (partner→R3HCC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	OR5D3P →	+0.120	+3.646	.005	.009	3	3
HNSC	AKR1B1P3 →	+0.252	+3.730	<.001	.004	3	3
READ	MIR549A →	+0.921	+4.653	<.001	.007	3	3
LUAD	H3P9 →	+0.336	+2.750	<.001	.003	3	3
SKCM	MIR6893 →	+0.245	+3.037	<.001	.003	3	3
UCEC	MIR6864 →	+0.409	+1.476	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,719 associations by consensus.

OR5D3P by R3HCC1L expression — STAD

Explore this box plot interactively →