R3HCC1L

Across TCGA cell cohorts, R3HCC1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,664 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible R3HCC1L-associated GO terms across cancer lineages are Positive regulation of maintenance of sister chromatid cohesion, Positive regulation of maintenance of mitotic sister chromatid cohesion, and Double-strand break repair. Each is linked with R3HCC1L in more than 14 cancer types. Because this analysis shows association rather than direction, both R3HCC1L-to-partner and partner-to-R3HCC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of maintenance of sister chromatid cohesion grouped by R3HCC1L-low versus R3HCC1L-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (R3HCC1L→partner) and Y-score (partner→R3HCC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of maintenance of sister chromatid cohesion →	+0.127	+0.614	.001	<.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.127	+0.614	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.065	+0.488	.001	.001	3	12
SOFT_TISSUE	Regulation of maintenance of sister chromatid cohesion →	+0.108	+0.565	.001	.003	2	13
SOFT_TISSUE	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.108	+0.565	.001	.003	2	13
BLOOD_Myeloma	Melanosome assembly →	+0.090	+0.915	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,664 associations by consensus.

Positive regulation of maintenance of sister chromatid cohesion by R3HCC1L expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →