QTRT2

Across TCGA pan-cancer cohorts, QTRT2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated QTRT2 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher QTRT2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated QTRT2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, LUAD, and PDAC are the cancer types where QTRT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.530	0.816	.002	40	view →
LUAD	DFS	Tertile	II,III,IV	0.960	0.772	.005	18	view →
PDAC	DFS	Median	III,IV	0.326	0.730	.008	5	view →
LSCC	DFS	Tertile	II,III,IV	0.873	0.539	.013	2	view →
GBM	DFS	Median	All	0.651	0.835	.008	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

QTRT2–HNSC (DFS)

Open the HNSC breakdown →