QTRT2

Across TCGA cell cohorts, QTRT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,562 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible QTRT2-associated GO terms across cancer lineages are tRNA wobble guanine modification, DNA recombination, and rRNA 5'-end processing. Each is linked with QTRT2 in more than 19 cancer types. Because this analysis shows association rather than direction, both QTRT2-to-partner and partner-to-QTRT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble guanine modification grouped by QTRT2-low versus QTRT2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QTRT2→partner) and Y-score (partner→QTRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA wobble guanine modification →	+0.294	+0.947	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	DNA recombination →	+0.097	+1.158	<.001	<.001	3	18
LUNG_NSCLC_LUSC	rRNA 5'-end processing →	+0.147	+0.668	<.001	.001	3	17
OVARY	Ribosome localization →	+0.117	+0.716	<.001	<.001	3	17
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.126	+0.660	<.001	.001	3	17
LUNG_NSCLC_LUSC	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.147	+0.668	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,562 associations by consensus.

tRNA wobble guanine modification by QTRT2 expression — BONE

Explore this box plot interactively →