Across TCGA pan-cancer cohorts, QTRT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated QTRT1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher QTRT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated QTRT1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

HNSC, CCRCC, and LSCC are the cancer types where QTRT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	III,IV	0.732	0.971	<.001	50	view →
CCRCC	DFS	Tertile	All	0.470	0.860	<.001	26	view →
LSCC	DFS	Quartile	All	1.000	0.274	.001	16	view →
PDAC	DFS	Median	IV	0.785	0.214	.006	9	view →
LUAD	DFS	Quartile	All	0.700	0.411	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: QTRT1 tumor-vs-normal RNA expression · all QTRT1 data types