Across TCGA patient cohorts, QTRT1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QTRT1-associated genes across cancer lineages are CD8+ Tem, CD4+ T-cells, and Plasma cells. Each is linked with QTRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both QTRT1-to-partner and partner-to-QTRT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QTRT1→partner) and Y-score (partner→QTRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tem →	+0.004	+4.744	<.001	.040	3	1
LGG	CD4+ T-cells →	+0.015	+6.380	<.001	.023	3	1
UCEC	Plasma cells →	-0.027	-3.279	.017	.011	2	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.268	.025	.011	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

QTRT1 survival (RNA) · tumor vs normal (RNA) · all QTRT1 data types